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Jim Harrison

James H. Harrison, Jr., MD, PhD is an Associate Professor and Director of the Division of Biomedical Informatics in the Department of Public Health Sciences at the University of Virginia, Director of Cancer Informatics for the University of Virginia Cancer Center, and co-Director of the NLM-funded Medical Informatics Training Program in collaboration with the Dept. of Systems and Information Engineering in the UVa School of Engineering & Applied Science. He has a secondary appointment in the Department of Pathology with a focus on clinical chemistry and clinical information systems, and also directs the PHS7070 "Introduction to Health Informatics" course in the Clinical Investigation Masters program. Jim has about 20 years of experience in clinical laboratory information systems management, clinical data analysis and World Wide Web development.

He was formerly a member of the Centers for Oncology and Pathology Informatics, the Center for Biomedical Informatics, and the Intelligent Systems Program at the University of Pittsburgh and there directed graduate courses in Python programming for medical informatics and XML/structured text markup.

Dr. Harrison is a member of the Diagnostic Intelligence and Health Information Technology Committee (DIHIT) of the College of American Pathologists, and chairs the DIHIT Standards and External Affairs Workgroup. He is also a member of the Orders and Observations Working Group of the HL7 standards organization, the Laboratory Domain of the IHE standards organization, and the Virginia state Health Information Technology Standards Advisory Committee. Jim's clinical interests include clinical chemistry, endocrinology and clinical pharmacokinetics. His informatics interests include temporal pattern recognition in clinical laboratory data, data warehousing and data mining, XML as a mechanism for structuring clinical and laboratory data, the influence of user interface on clinical decision making, and communication infrastructures for scientific and medical collaboration. He also develops and supports CiteInPages, a set of Applescripts that integrate the BibDesk reference manager with Apple's Pages word processor, and the LabScanner clinical data analysis program for the Mac and PC, which is available free of charge to the laboratory medicine community.

Other resources, including links to Dr. Harrison's open source software, are on the HomePage of this server.

Email: james-dot-harrison-at-virginia-dot-edu

Current Funding

  • CMS Healthcare Innovation Award 1C12012001705, Rapid Response Supportive and Palliative Care Program for Patients with Advanced Cancer. Co-investigator and lead of Project 1, "MyCourse." MyCourse will gather clinical and patient-reported data from multiple sources and integrate it in a display that helps care providers proactively identify opportunities for evidence-based palliative care interventions that improve the quality of care, increase length of survival, and reduce costs.
  • NCI 2U01 CA091654-06, Tissue Procurement and Processing for Molecular Analysis. Co-investigator with responsibility for the biorepository information system. The goals of this project are to provide samples of human tissue to the Cooperative Human Tissue Network and to provide a tissue microarray production facility to support extramural research efforts of the NCI.
  • NHLBI 2P01HL055798, Immune Cells in Atherosclerosis and Vascular Disease, Human phenotyping and immune cell core. Co-investigator supervising cell phenotyping core facility data management.
  • NCI 2-P30CA044579-21, UVA Cancer Center Support Grant. Co-investigator and lead of Cancer Informatics. The Cancer Informatics Team supports the Cancer Center Office for Clinical Research and provides informatics infrastructure for opening, management, and reporting of clinical trials.

Selected Publications/Presentations (Detailed Curriculum Vitae, 2012)

Gerber, M, Brown, D, and J Harrison. Automatic formalization of clinical practice guidelines. In: AAAI 2012 Fall Symposium on Information Retrieval and Knowledge Discovery in Biomedical Text; AAAI Technical Report FS-12-05:14-19.

Batal, I, Fradkin, D, Harrison, J, Moerchen, F, and M Hauskrecht. Mining recent temporal patterns for event detection in multivariate time series data. Proceedings of the 18th ACM SIGKDD International Conference on Knowledge Discovery and Data Mining (KDD '12):280-288, 2012.

Harrison, J.H., Jr. Management of pathology information systems. in: Laboratory Administration for Pathologists, Wagar, E.A., Horowitz, R.E., and Siegel, G.P., eds. Chicago: CAP Press, 2011.

Harrison, J.H., Jr., J. Roberts, K. Scully, and J.A. Lyman. Rapid development of research databases with Web access, flexible schemas, and linkage to local data resources. Presented at the AMIA Summit on Clinical Research Informatics, San Francisco, March 9 - 11, 2011.

Post, A.R., and J.H. Harrison. Concept similarity in publications precedes cross-disciplinary collaboration. Proc AMIA Symp 2008:606-610.

Harrison, J.H., Jr. Introduction to the mining of clinical data. Clin Lab Med 28(1):1-7, 2008.

Lyman, J.A., K. Scully and J.H. Harrison, Jr. The development of healthcare data warehouses to support data mining. Clin Lab Med 28(1):55-71, 2008.

Siadaty, M.S., and J.H. Harrison, Jr. Multi-database mining. Clin Lab Med 28(1):73-82, 2008.

Post, A.R., and J.H. Harrison, Jr. Temporal data mining. Clin Lab Med 28(1):83-100, 2008.

Harrison, J.H., Jr. and R.D. Aller. Regional and national healthcare data repositories. Clin Lab Med 28(1):101-117, 2008

Jackson, B., and J.H. Harrison. Clinical laboratory informatics. in: Tietz Fundamentals of Clinical Chemistry, 6th Ed. Burtis, C.A., Ashwood, E.R., and Bruns, D.E., eds. St. Louis: Elsevier Saunders, 2008.

Post, A.R., A.N. Sovarel and J.H. Harrison. Abstraction-based temporal data retrieval for a clinical data repository. Proc AMIA Symp 2007:603-607.

Post, A.R., and J.H. Harrison. PROTEMPA: A method for specifying and identifying temporal sequences in retrospective data for patient selection. J Am Med Inform Assoc 14(5):674-683, 2007.

Saadawi, G., and J.H. Harrison. Definition of an XML markup language for clinical laboratory procedures (CLP-ML) and comparison with generic XML markup. Clin Chem 52:1943-1951, 2006.

Post, A.R., and J.H. Harrison. Data acquisition behaviors during inpatient results review: implications for problem-oriented data displays. Proc AMIA Symp 2006:644-648.

Sedarat, F., F.E. Craig and J.H. Harrison. A software tool to enhance flow cytometry quality assurance and interpretation. Presented at the ACLPS 2005 meeting, Pittsburgh PA, June 10, 2005.

Carter, A.B., J.H. Harrison and J.A. Kant. Database design for a molecular pathology laboratory. Presented at the ACLPS 2005 meeting, Pittsburgh PA, June 10, 2005. Am J Clin Pathol 124:457, 2005.

Harrison, J.H., Jr. A framework for integrating time into clinical laboratory quality assurance and clinical process control. Presented at the Academy of Clinical Laboratory Physicians and Scientists (ACLPS) 2005 meeting, June 11, 2005, Pittsburgh PA, as part of a focus session titled "Expert systems in clinical laboratory data analysis and quality assurance."

Harrison, J.H., Jr. Information delivery methods. in: Lewis, D., Eysenbach, G., Kukafka, R., Stavri, Z., Jimison, H., Eds. Consumer Health Informatics: Informing customers and improving health care. New York:Springer Science+Business Media, Inc., 2005.

Harrison, J.H., Jr. A framework for integrating time into clinical laboratory quality assurance and clinical process control studies. Presented at LabAutomation05, San Jose CA, Feb 2005.

Post, A.R. and J.H. Harrison. A Two-Stage Temporal Abstraction Method for Pattern Detection in Clinical Laboratory Data. Presented at the APIII Conference, Pittsburgh PA, Oct, 2004.

Post, A.R. and J.H. Harrison. Web-based implementation of a modular, general purpose temporal abstraction framework for pattern identification in clinical laboratory data. Presented at the APIII Conference, Pittsburgh PA, Oct, 2003. Arch Pathol Lab Med 128:1102, 2004.

Saadawi, G. and J.H. Harrison. A lightweight XML editor for clinical laboratory procedure manuals. Presented at the APIII Conference, Pittsburgh PA, Oct, 2003. Arch Pathol Lab Med 128:1104, 2004.

Harrison, J.H., Jr. Pathology Informatics Questions and Answers from the University of Pittsburgh Pathology Residency Informatics Rotation. Arch Pathol Lab Med 128:71-83, 2004.

Harrison, J.H. Jr., and J. Stewart. Training in pathology informatics: implementation at the University of Pittsburgh. Arch Pathol Lab Med 127:1019-1025, 2003.

Henricks, W.H., P.J. Boyer, J.H. Harrison, J.M. Tuthill, and J.C. Healy. Informatics training in pathology residency programs: proposed learning objectives and skill sets for the new millennium. Arch Pathol Lab Med 127:1009-1018, 2003.

Schubert, E., Gross, W., Gilbertson, J., Harrison, J., and M. Becich. Anatomic Pathology Laboratory Information systems. In: Modern Surgical Pathology, Weidner, N., Cote, R.J., Suster, S., and Weiss, L.M., Eds. Philadelphia: Saunders, 2003.

Harrison, J.H., Jr. Outcomes Research. In: Information Technology in Transfusion Medicine. S.H. Butch and M. Simpson, Eds. AABB Press: Bethesda, MD, 2002.

Post, A.R., and J.H. Harrison. An Enhanced Framework for Pattern Detection in Clinical Laboratory Data. Proc AMIA Symp 2002:1134.

Post, A.R. and J.H. Harrison, Jr. Pattern detection in clinical laboratory data for patient identification and quality assurance. Proc AMIA Symp 2001:1000.

Davie, J., J.H. Harrison and J.A. Kant. Molecular diagnostics LIMS functions in an anatomic pathology LIMS environment: experience and challenges (a case study). Proc AMIA Symp 2001:817.

Harrison, J.H., Jr. Pathology and the electronic medical record: challenges and opportunities for the future. Advance for Administrators of the Laboratory. 8(9):30-37, 1999.

Harrison, J.H., Jr., and Petrie Rainey. Identification of patients for pharmacologic review by computer analysis of clinical laboratory drug concentration data. Am. J. Clin. Pathol., 103:710-717, 1995.

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